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Brompheniramine is an antihistamine medication commonly used to treat allergy symptoms. It belongs to the class of first-generation antihistamines, which work by blocking the effects of histamine, a substance produced by the body during allergic reactions. Histamine causes symptoms such as sneezing, runny nose, itchy or watery eyes, and itching of the throat or nose.
Key Characteristics of Brompheniramine:
- Chemical Name: Brompheniramine maleate
- Formulations: Available in tablets, liquid syrups, and sometimes in combination with other medications
- Onset of Action: Usually begins to work within 15-30 minutes after ingestion
- Duration: Effects can last for 4-6 hours, depending on the dose and formulation
Uses:
- Relief of allergic rhinitis (hay fever)
- Treatment of cold symptoms
- Relief of urticaria (hives) and other allergic skin conditions
- Sometimes used to reduce itching and sneezing caused by allergies
How it Works:
Brompheniramine blocks H1 histamine receptors on cells in the body, preventing histamine from exerting its effects. This alleviates allergy symptoms but can also cause side effects due to its action on other parts of the nervous system.
Common Side Effects:
- Drowsiness or sedation
- Dizziness
- Dry mouth, nose, or throat
- Dizziness
- Blurred vision
- Urinary retention
Precautions:
- Due to its sedative effects, caution should be exercised when driving or operating machinery.
- Not recommended for use in young children without medical advice.
- Should be used cautiously in elderly individuals, who may be more sensitive to side effects.
- Can interact with other CNS depressants, such as alcohol, sedatives, or tranquilizers.
Summary:
Brompheniramine is an effective antihistamine for managing allergy symptoms, but its sedative properties mean it should be used carefully. It is generally available over the counter and often included in multi-symptom cold remedies. If you need more detailed information, such as specific dosages or contraindications, consulting a healthcare professional or the medication’s prescribing information is recommended.



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